"Ataque de Pánico! (Spanish for Panic Attack!) is a 2009 Uruguayan sci-fi short film, directed by independent filmmaker Fede Álvarez." (from Wikipedia). I must add that "Ataque de Pánico!" is a GREAT short developed with a 300$ budget.

The big news is that the producer from Uruguay who uploaded a short film to YouTube in November 2009 has been offered a $30m (£18.6m) contract to make a Hollywood film. (source: BBC - YouTube video leads to Hollywood contract)

I love when the Internet helps independent artists to major success.